I think Catwoman pretty much killed Halle Berry's career. That's one that springs to mind.
It's also a shame how Geena Davis has just gone from the movie world because she was a very good actress.
Why anyone thought Catwoman was a good idea is beyond me... Mind you, that's not the only dodgy career decision Halle Berry has made. The only decent thing she's ever done is that sex scene in Monster's Ball!