When you pick it up, I'm guessing you're in a car, I'd place some newspaper on the floor by your feet, and place a blanket on you knees and let her rest and she'll soon settle.
Once you get home, take it out for toilet, and let it sniff each room one by one, so it gets to learn what rooms are what. Choose a room for it's bed and stick to it, along with all the feeding times.
We crate trained ours, and she is only 14 weeks old at the moment, so we will crate her after a feed for 20 mins, before toiletting, as they hate to soil their beds. Also crated her for 30 mins if we were cooking etc, so she got used to it, and now she will go into her crate if we say "bed".
Make sure you praise when she does good things, and toilets in the right place, but don't tell her off... When she bites you, make sure you "yelp", and once she pauses a little to praise her, so she learns that biting you isn't good, but toys are good =] If it toilets in the wrong place, just ignore it, clean it up, but use a non-ammonia based solution from pet shops =]
Also, make sure you read the back of treats and toys to make sure that you're feeding it the right things, as I know that Pedigree Tubos are for 4 months old and over.
Get it used to a soft collar, but remember to take it off whenever she is left unattended and at night time. It will cry the first few nights, but don't go and see it, just try to distract yourself. If you are going to be locking it in it's crate, during the night you will have to let it out every 2 or 3 hours for toiletting.
Just remember, the first 3 years of a dogs life are the hardest as they are like infants from birth till 8 months, and adolescents from 8 months till 3 years. After the 1st year, as long as everyone is being consistant with the training and praise, you guys should have clicked it by then =]
Oh also, although it won't be able to be walked until it is 11 or 12 weeks old, make sure you take it everywhere with you... including supermarkets... Carry it =] We did that with our Holly, and the only shop we got kicked out of was Booths, but Sainsburys loved her, and we allowed a few kids to give her treats, just to socialise her with every kind of person and situation. Before it reaches 14 weeks of age is the best time to socialise a puppy.
Hope this helps... and I hope the breeder you are getting it off give you a toxic food list, and help with puppy food, training etc