I don't think they'll make it Cameron because the storyline will get too repetitive and it'll take the focus off his relationship with Leela. Also, surely Sienna knows that Cameron's in the village because she's friends with Leela. Obviously Nico being Cameron's daughter would be the nicest outcome but Sienna isn't really destined for nice outcomes.
One plot detail that makes me suspect Patrick is the fact that he maintained in close contact with Nico's adoptive parents; he even has photos. However he doesn't want to see Nico in person and told her to get out of town. Seeing as Patrick doesn't really come across as a loving grandparent, it wouldn't make sense for him to keep that contact. However if he was the father, presumably paternal instinct would mean that he kept in contact even if he hated the child.