In one sense, the idea of the Others and the other house is pretty similar to the House Next Door from BB7.
However, I do think that the idea of two continuing sets of housemates where one set get to be nominated and nominate and the other set are immune but get to swap with members of the other set is pretty novel.
Ultimately it will depend on how much say the public get about the final status of the Others. I think it would be grossly unpopular if, at some point, BB just says all the Others have failed and must now leave the house for good.
That would mean that public favourites could end up leaving without the public having any say in the matter at all which would be counter to the fundamental "You Decide" ethos of the show. If that happens then it really would be a Game Changer but one very much for the worst, IMO.
On the other hand, if the intention is that, ultimately, the two houses will merge and everyone becomes a housemate then the Others will actually have had a huge advantage as they will have been able to dodge nominations for the duration of their stay in the Other house. One could argue that that, also, is a bit of a game changer!