it nearly beats Midsomer Murders (yes, know it's not a soap) but they have an average of 2.5 murders per episode - so far approx. 110 episodes = 275 murders
Plus depending how you interpret 'killed by' most HO deaths are at the hands of somebody - be it directly (such as Sean) or indirectly (Rachel by someone drink driving) - with the exception of Jade (Hodgkins Lymohoma) all other deaths in past two years of regular characters are down to someonelse's bad actionss